Japanese scientist Yoshinori Ohsumi smiles in front of a sign congratulating him for winning this year's Nobel Prize in medicine at the Tokyo Institute of Technology campus in Yokohama, south of Tokyo, Monday, Oct. 3, 2016. Ohsumi was awarded this year's Nobel Prize in medicine on Monday, Oct. 3, for discoveries related to the degrading and recycling of cellular components. The Karolinska Institute honored Ohsumi for "brilliant experiments" in the 1990s on autophagy, the machinery with which cells recycle their content. Disrupted autophagy has been linked to various diseases including Parkinson's, diabetes and cancer, the institute said. (Junko Ozaki/Kyodo News via AP)