(FILES) In this file photo taken on August 28, 2019 an entry sign to the Johnson & Johnson campus shows their logo in Irvine, California. - The Johnson & Johnson vaccine is highly effective against severe Covid-19, including against the South African and Brazil variants, new documents released by the US Food and Drug Administration showed on February 24, 2021. In large clinical trials, the vaccine efficacy against severe disease was 85.9 percent in the United States, 81.7 percent in South Africa, and 87.6 percent in Brazil. (Photo by Mark RALSTON / AFP)