Japanese scientist Yoshinori Ohsumi scratches his head as he reacts photographers' request to smile following a news that he won this year's Nobel Prize in medicine at the Tokyo Institute of Technology campus in Yokohama, south of Tokyo, Monday, Oct. 3, 2016. Ohsumi was awarded this year's Nobel Prize in medicine on Monday, Oct. 3, for discoveries related to the degrading and recycling of cellular components. (Junko Ozaki/Kyodo News via AP)